Serena Duchi
ISOF-CNR,Italy
Biography
Dr. Serena Duchi got her PhD in Molecular and Cellular Physiology in 2009 (Italy-USA program, University of Bologna, Italy). During her post doc in IFOM-IEO Cancer Center in Milan (Italy) she acquired a strong background in the regulation of tumor suppression and endocytosis to design new chemotherapeutic drugs. She then specialized in the treatment of musculoskeletal tumors at the Rizzoli Orthopaedics Institute (Bologna-Italy) where she leads as research fellow for different projects:
• identification of the differentiation capabilities, onset of senescence and tumorigenic signal transduction in mesenchymal stem/stromal cells (MSC) isolated and expanded from osteosarcoma patients and from healthy subjects;
• use of MSC for the transport of chemotherapeutic drugs as innovative therapeutic approach for the treatment of OS;
• use of MSC in 3D bioprinting based regenerative medicine for osteo-chondral defects.
She has a passion and strong knowledge in different imaging techniques for epifluorescence, confocal and time-lapse microscopy, FRET, TIRF, Light-Sheet Microscopy.
Abstract
Abstract : Mesenchymal Stromal Cells and therapeutic nanoparticles as multimodal treatment of osteosarcoma